Clinical Trials

3 studies in Alcohol and tobacco dependence

1. Varenicline Treatment for Active Alcoholic Smokers Rochester, MN View Summary
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   Varenicline Treatment for Active Alcoholic Smokers

   Location:

   Rochester, MN

   Trial status:

   Open for Enrollment

   Why is this study being done?

   Seventy smokers who are currently alcohol dependent will be enrolled to this study. If found to be study eligible they will be randomized to either active varenicline or placebo for 12 weeks. During these two weeks, they will be seen either weekly or biweekly. At the end of treatment, they will be followed up for an addition 12 weeks. Their last study visit will be 6 months after randomization.

   NCT ID:

   NCT01347112

   IRB Number:

   10-008559

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   Who can I contact for additional information about this study?

   Rochester: Judy A. Trautman, RN 507-266-1944
                       Richard A. Morris, BA 507-266-1944
   
   
   

2. Support Person Effectiveness Study to Promote Smoker Utilization of the QUITPLAN Helpline Rochester, MN View Summary
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   Support Person Effectiveness Study to Promote Smoker Utilization of the QUITPLAN Helpline

   Location:

   Rochester, MN

   Trial status:

   Open for Enrollment

   Why is this study being done?

   This study is being done to learn the helpfulness of a telephone-based program for support persons living in MN who are worried about a cigarette smoker living in MN. This study will help support person learn new ways to be supportive as well as encourage a smoker to call the QUITPLAN Helpline. The QUITPLAN Helpline is the tobacco Helpline for the state of Minnesota. Research shows that Helpline?s are an effective way for smokers to quit or make a plan to quit. The person you want to support does not need to be interested in or even thinking about quitting smoking in order for you to be in the study. If the smoker does choose to call QUITPLAN, they are eligible for free services (counseling and/or nicotine replacement therapy) for seven months. The seven months starts on the date of support person enrolling into our study.

   IRB Number:

   11-001796

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   Who can I contact for additional information about this study?

   Christina Smith 800.957.2950 toll-free 507.538.8210 local supportpersonstudy@mayo.edu

3. MRS Probe Study of Alcohol Rochester, MN View Summary
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   MRS Probe Study of Alcohol

   Location:

   Rochester, MN

   Trial status:

   Open for Enrollment

   Why is this study being done?

   This protocol will investigate the neurobiological underpinnings of alcohol craving in recently detoxified alcoholic drinkers utilizing novel functional brain imaging. This clinical magnetic resonance spectroscopy (MRS) study will investigate whether glutamate and other brain metabolites correlate to measures of alcohol craving severity

   NCT ID:

   NCT01679444

   IRB Number:

   12-003693

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   Who can I contact for additional information about this study?

   Rochester: Lee J Gunderson, BS 507-255-6725
                       Michelle K Skime, BA 507-255-0501