Clinical Trials

3 studies in Healthy Volunteers

1. Establishment of Normal Ranges for Newly Developed Cardiovascular Assays Rochester, MN View Summary
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   Establishment of Normal Ranges for Newly Developed Cardiovascular Assays

   Location:

   Rochester, MN

   Trial status:

   Open for Enrollment

   Why is this study being done?

   This research study is being done to determine levels of proteins that are normally present in the blood and urine of healthy individuals so as to compare to those levels in patients with heart disease.
   
   Normal blood and urine will be analyzed for levels of proteins and cardiac peptides which are affected by heart disease in the elderly. We are trying to determine if there are normal age-related changes when heart disease is not involved.

   IRB Number:

   718-05

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   Who can I contact for additional information about this study?

   If you are interested in participating in this study or would like additional information, please contact Sharon Sandberg or Dr. Fernando Martin at (507) 284-4838.

2. Physiologic Effects of Sleep Restriction Rochester, MN View Summary
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   Physiologic Effects of Sleep Restriction

   Location:

   Rochester, MN

   Trial status:

   Open for Enrollment

   Why is this study being done?

   Evidence suggests a relationship between sleep deprivation and cardiovascular disease. Voluntary sleep restriction is common, with 28% of the US adult population reports getting 6 or fewer hours of sleep per night, and those who do are 24% more likely to have cardiovascular disease and have twice the risk of hypertension. Insufficient sleep may conceivably be one of the most common, and most preventable, cardiovascular risk factors. The investigators wish to determine whether 9 nights of modest sleep restriction results in activation of cardiovascular disease mechanisms, thus potentially increasing the risk of cardiovascular disease. The investigators will combine our cardiovascular studies with state-of-the art sleep monitoring and neurocognitive tests to provide unambiguous data on the neurologic effects of sleep restriction. Together, the investigators findings will help explain whether the reduced sleep duration in the general population may be contributing to the current epidemic of cardiovascular disease, and suggest strategies to reduce this risk.

   NCT ID:

   NCT01433315

   IRB Number:

   11-002121

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   Who can I contact for additional information about this study?

   Rochester: Diane E Davison, MA, RN 507-255-8794
                       
   
   
   

3. Code Status Video in the Intensive Care Unit: Video Assisted Patient Education Rochester, MN View Summary
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   Code Status Video in the Intensive Care Unit: Video Assisted Patient Education

   Location:

   Rochester, MN

   Trial status:

   Open for Enrollment

   Why is this study being done?

   This is a single-center, randomized control trial of a code status video as an educational tool in the intensive care unit. Subjects are stratified by patient or surrogate and are randomized to either watch an educational video on code status or not watch the video. They are then asked knowledge base questions regarding code status as well as questions pertaining to comfort regarding code status. Participants randomized to watch the video are also asked questions related to acceptance of the video.

   NCT ID:

   NCT01610076

   IRB Number:

   10-003628

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   Who can I contact for additional information about this study?

   Rochester: Richard Hinds, MS 507-538-4344