Clinical Trials

1 studies in Intracerebral hemorrhage

1. Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage Phase III Jacksonville, FL Scottsdale and Phoenix, AZ View Summary
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   Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage Phase III

   Location:

   Jacksonville, FL Scottsdale and Phoenix, AZ

   Trial status:

   Open for Enrollment

   Why is this study being done?

   The overall objective of this Phase III clinical trial is to obtain information from a population of 500 ICH subjects with intraventricular hemorrhage (IVH), representative of current clinical practice and national demographics of ICH regarding the benefit (or lack thereof) of IVH clot removal on subject function as measured by modified Rankin Scale (mRS). This application requests funding for five years to initiate a Phase III randomized clinical trial (RCT) testing the benefit of clot removal for intraventricular hemorrhage. The investigators propose to compare extraventricular drainage (EVD) use plus recombinant tissue plasminogen activator (rt-PA, Cathflo® Activase® Genentech, Inc., San Francisco, CA) with EVD+ placebo in the management and treatment of subjects with small intracerebral hemorrhage (ICH) and large intraventricular hemorrhage (IVH defined as ICH < 30 cc and obstruction of the 3rd or 4th ventricles by intraventricular blood clot).

   NCT ID:

   NCT00784134

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   Who can I contact for additional information about this study?

   
   Scottsdale: Deborah Unger 480-342-3484
                       Maria Aguilar, MD 480-342-3370
   Jacksonville: Alexa Richie 904-953-7839
                       William Freeman, MD 904-953-7229