Clinical Trials

3 studies in Constipation

1. A Phase 2 Study to Evaluate Pharmacodynamics of YKP10811 in Patients With Chronic or Functional Constipation Rochester, MN View Summary
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   A Phase 2 Study to Evaluate Pharmacodynamics of YKP10811 in Patients With Chronic or Functional Constipation

   Location:

   Rochester, MN

   Trial status:

   Open for Enrollment

   Why is this study being done?

   If the participant fulfills the initial eligibility criteria, the patient will be randomized to 1 of the active treatment groups or placebo. During the treatment period, patients will receive study medication once daily for 8 days. Patients will undergo scintigraphic assessment of gastric, small bowel and colonic transit of solids over the 48-hour period. Patients will be males or females, 18 through 65 years of age with a body mass index (BMI) of 19 through 40 kg/m2, with Chronic Constipation or Functional Constipation and no evidence of evacuation disorder as assessed by the Investigator and meet all the inclusion criteria and none of the exclusion criteria.

   NCT ID:

   NCT01523184

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   Who can I contact for additional information about this study?

   Rochester: Amy Boldingh 507-538-6599
                       
   
   
   

2. Phase 2 Study to Evaluate Safety and Efficacy of RM-131 Administered to Patients With Chronic Constipation Jacksonville, FL Scottsdale and Phoenix, AZ View Summary
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   Phase 2 Study to Evaluate Safety and Efficacy of RM-131 Administered to Patients With Chronic Constipation

   Location:

   Jacksonville, FL Scottsdale and Phoenix, AZ

   Trial status:

   Open for Enrollment

   Why is this study being done?

   The purpose of this study is to evaluate safety and tolerability as well as the effects of RM-131 on colonic transit, bowel consistency, bowel habits, abdominal pain, and other abdominal symptoms in patients with chronic constipation.

   NCT ID:

   NCT01781104

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   Who can I contact for additional information about this study?

   
   Scottsdale: Susanna Murphy 480-301-4319
                       
   Jacksonville: Geraldine Simpson 904-953-8505
                       
   

3. 12 Week Efficacy and Safety Trial Followed by a 4 Week Withdrawal Period for Patients With Chronic Idiopathic Constipation Rochester, MN View Summary
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   12 Week Efficacy and Safety Trial Followed by a 4 Week Withdrawal Period for Patients With Chronic Idiopathic Constipation

   Location:

   Rochester, MN

   Trial status:

   Open for Enrollment

   Why is this study being done?

   12 Week Efficacy and Safety Trial Followed by a 4 Week Withdrawal Period for Patients with Chronic Idiopathic Constipation.

   NCT ID:

   NCT01833065

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   Who can I contact for additional information about this study?

   - Mayo Clinic Cancer Center - Phone: 507-538-7623 - Research Volunteer Program - Phone: 1-800-664-4542 (toll-free) Email: clinicaltrials@mayo.edu - International Research - Phone: 507-284-8884 Email: intl.mcr@mayo.edu