Clinical Trials

5 studies in Obesity

1. Effects of Calorie Restriction on Accumulation of Old, Modified Proteins in Abdominally Obese Adults Rochester, MN View Summary
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   Effects of Calorie Restriction on Accumulation of Old, Modified Proteins in Abdominally Obese Adults

   Location:

   Rochester, MN

   Trial status:

   Open for Enrollment

   Why is this study being done?

   This study is being done to understand the effects of calorie restriction and weight loss on muscle protein metabolism in adult men and women.

   NCT ID:

   NCT01497106

   IRB Number:

   11-006181

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   Who can I contact for additional information about this study?

   Rochester: Deborah Sheldon 507-255-8082
                       
   
   
   

2. Feasibility of Use of BariCare App in Pre-bariatric Surgery. Rochester, MN View Summary
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   Feasibility of Use of BariCare App in Pre-bariatric Surgery.

   Location:

   Rochester, MN

   Trial status:

   Open for Enrollment

   Why is this study being done?

   This current study aims to evaluate the efficacy of engagement modules in preparing patients for bariatric surgery. With the help of the Center for Innovation (CFI), a smartphone app (Android and Apple compatible) has been created that will assist in both educating and engaging patients to develop and maintain healthy lifestyle modifications. Our goal is to create a cost-effective, smartphone-based platform that serves to not only efficiently educate but to also verify competence and keep our patients engaged during the lengthy pre-bariatric surgery process.

   NCT ID:

   NCT01708135

   IRB Number:

   12-005535

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   Who can I contact for additional information about this study?

   Rochester: Paul Lorentz, RN 507-538-1595
                       
   
   
   

3. Effect of Vitamin D Supplementation on Endothelial Function in Obese Adolescents Rochester, MN View Summary
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   Effect of Vitamin D Supplementation on Endothelial Function in Obese Adolescents

   Location:

   Rochester, MN

   Trial status:

   Open for Enrollment

   Why is this study being done?

   Vitamin D deficiency has been linked to endothelial dysfunction in adults. Obese adolescents have a high prevalence of Vitamin D deficiency as well as evidence of endothelial dysfunction. Our hypothesis is that supplementation of Vitamin D deficient adolescents with Vitamin D would lead to improvement in endothelial dysfunction.

   NCT ID:

   NCT01746264

   IRB Number:

   12-006349

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   Who can I contact for additional information about this study?

   Rochester: Asma Javed, MBBS 507-284-3300
                       
   
   
   

4. Pivotal Aspiration Therapy With Adjusted Lifestyle Therapy Study Rochester, MN View Summary
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   Pivotal Aspiration Therapy With Adjusted Lifestyle Therapy Study

   Location:

   Rochester, MN

   Trial status:

   Open for Enrollment

   Why is this study being done?

   The Aspiration process works by "correcting" meal portions after eating by removing the food left in your stomach 20 minutes after your meal, reducing the number of calories absorbed by your body. This is done through a tube placed through the abdomen into the stomach with a small valve attached at the surface of your skin. An aspiration system will attach to that valve after each major meal of the day and allow you to remove a portion of that meal. During this study you will also be provided with Lifestyle therapy which includes behavioral therapy, diet and physical activity education. This Lifestyle therapy will also be provided to the participants who do not receive the AspireAssist so that the two groups can be compared and the benefit of aspiration for weight loss can be determined.

   NCT ID:

   NCT01766037

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   Who can I contact for additional information about this study?

   Rochester: Tamera Roberson 507-255-8621
                       
   
   
   

5. Muscle Protein Metabolism in Obesity Scottsdale and Phoenix, AZ View Summary
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   Muscle Protein Metabolism in Obesity

   Location:

   Scottsdale and Phoenix, AZ

   Trial status:

   Open for Enrollment

   Why is this study being done?

   Obesity is associated with reduced adenosine triphosphate (ATP) turnover in skeletal muscle, a condition that can impair muscle metabolism. The proposed research will discover mechanisms responsible for decreased content in mitochondrial proteins as well as in protein β-F1-ATPase, which is directly responsible for ATP assembly, in the muscle of obese individuals. This research will further examine the effectiveness of interventions, such as increased plasma amino acid availability and exercise, to increase the rate of production of mitochondrial proteins as well as that of β-F1-ATPase in the muscle of obese individuals. The findings will help to develop appropriate interventions to improve muscle ATP turnover and metabolism in obese people.

   NCT ID:

   NCT01824173

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   Who can I contact for additional information about this study?

   
   Scottsdale: Early Jennifer, RN 480-301-4142
                       Christos Katsanos, PhD 480-301-6015