Clinical Trials

Collecting and Storing Samples of Bone Marrow and Blood From Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma

Location:

Rochester,  MN

Trial status:

Open for Enrollment

Why is this study being done?

OBJECTIVES:

- Establish a mechanism to bank specimens of tumor cells and host germline DNA from patients with acute lymphoblastic leukemia (ALL) or non-Hodgkin lymphoma at first and subsequent relapse.

- Make these specimens available to qualified researchers to study the biology of ALL.

OUTLINE: This is a multicenter study.

Patients undergo collection of bone marrow and peripheral blood at diagnosis of relapse and/or at the end of the first month of treatment.

Patients are followed periodically for up to 10 years.

PROJECTED ACCRUAL: Not specified.

Who is eligible to participate?

DISEASE CHARACTERISTICS:

- Diagnosis of acute lymphoblastic leukemia (ALL) or prior history of non-Hodgkin lymphoma

- In first or subsequent marrow relapse with ≥ 25% blasts in bone marrow and/or peripheral blood

- Bone marrow and/or peripheral blood samples (≥ 5 mL) required at the time of diagnosis of relapse

PATIENT CHARACTERISTICS:

- Not specified

PRIOR CONCURRENT THERAPY:

- No concurrent systemic antileukemic treatment administered for current relapse

- Intrathecal chemotherapy allowed

- On-therapy relapse allowed

Last updated: 11/03/2012

NCT ID: NCT00897325

IRB Number:07-007836