Mayo Clinic

Clinical Trials

Study of BMS-754807 Combined With Letrozole or BMS-754807 Alone in Patients With Hormone Receptor-Positive Breast Cancer and Resistance to Non-Steroidal Aromatase Inhibitors

Location:

Trial status:

Inactive

Why is this study being done?

The purpose of this study is to evaluate oral doses of BMS-754807 in combination with letrozole or BMS-754807 alone are safe and efficacious in locally advanced or metastatic hormone receptor positive breast cancer subjects who have progressed with prior non-steroidal aromatase inhibitor treatment.

Who is eligible to participate?

Inclusion Criteria:

- Postmenopausal women with hormone receptor-positive and HER-2 negative breast cancer

- Disease progression following non-steroidal aromatase inhibitor treatment

Exclusion Criteria:

- Known symptomatic brain metastasis

- Medical condition requiring chronic steroids

- History of Type 1 or 2 Diabetes

- Uncontrolled or significant cardiovascular (CV) disease

- Concomitant second malignancies

Last updated: 03/28/2013

NCT ID:

NCT01225172