IRB Number:

434-03

Trial Status:

Open for Enrollment

Phase: I

Why is this study being done?

This study will help us determine whether certain genetic mutations, more than others, are a cause of more severe disease in primary hyperoxaluria. This study is a more complete DNA test than the routine clinical test.

Who is Eligible to Participate in the Study?

You may be eligible to participate if:
-- You have been diagnosed with primary hyperoxaluria, OR
-- You have a family member diagnosed with primary hyperoxaluria

Maximum Age:

100

What is Involved With this Study?

During your study visit, we will draw two tubes tubes, about four teaspoonfuls (3 teaspoons for children), of blood from your arm to obtain white blood cells. These white blood cells will be used as a source of DNA for genetic testing. We will use the isolated DNA to try to identify the gene that is defective in primary yyperoxaluria by comparing it with the structure of genes in normal individuals, patients with primary hyperoxaluria, and family members of primary hyperoxaluria patients.

How long will the Study run?

You will be in this study for only one visit.

Who can I Contact for Additional Information on this Trial?

E-mail: Hyperoxaluriacenter@mayo.edu
Phone: 800-270-4637

What is/are the Locations of this Clinical Trial?

• Rochester, MN

Last updated: 01/12/2009