IRB Number:

07-002656

Trial Status:

Open for Enrollment

Phase: II

Why is this study being done?

The purpose of this study is to find out if the use of olive oil in your daily diet will improve endothelial function.

Who is Eligible to Participate in the Study?

• You are healthy


• You have been diagnosed with cardiovascular disease


• You have risk factors for cardiovascular disease; diabetes, high blood pressure, hyperlipidemia, smoking, family history of cardiovascular disease.

Minimum Age:

18

Maximum Age:

99

What is Involved With this Study?

The purpose of this study is to find out if the use of olive oil in your daily diet will improve endothelial function. Endothelial dysfunction is when the tissue lining in the arteries is not functioning correctly. To determine if you have endothelial dysfunction you will have a special test called EndoPAT. This is a non invasive test that will take about 20 minutes. If you qualify after the EndoPAT test you will have be asked to complete a questionnaire and to do a blood draw. The minimum appointment time is 30 minutes and the maximum appointment time is 1.5 hours. You will also need to fast for 4 hours prior to testing.

If you qualify you will receive either a 4 month supply of 'enhanced' olive oil or placebo. The daily intake will be 2 Tablespoons. After the 4 months you will be asked to do another EndoPAT test, a blood draw and a questionnaire.

How long will the Study run?

Four Months

Who can I Contact for Additional Information on this Trial?

Jasmine A. Sexton, Study Coordinator
sexton.jasmine@mayo.edu (e-mail corresondence preferred)
507-538-4665

What is/are the Locations of this Clinical Trial?

• Rochester, MN

Last updated: 08/31/2009