IRB Number:

1399-05

Trial Status:

Open for Enrollment

Phase: II

Why is this study being done?

This research study is being done to see if treatment for esophageal cancer can be done using endoscopy. The standard method of treating this type of cancer is surgical removal of the esophagus. The study will determine if removing just the cancer with endoscopy is enough treatment or if the addition of another treatment called photodynamic therapy (treatment with a red light and a drug called sodium porfimer) is needed.

Who is Eligible to Participate in the Study?

Early esophageal cancer in Barrett's Esophagus in patients not eligible for surgical or radiological therapy. Participants must be have oral intake of greater than 1700 calories a day. No history of cancer within the past 5 years. And have no history of extensive prior esophageal surgery (example: esophagectomy).

Minimum Age:

18

What is Involved With this Study?

Screening visit which will last 1 - 2 days, if assigned to photodynamic therapy, there will be a 3 day visit for treatment. Participants must return for a 1 day visit every three months for one year.

How long will the Study run?

Participants must return for a 1 day visit every three months for one year.

Who can I Contact for Additional Information on this Trial?

Complete Request Form for Cancer Clinical Trial Information at Mayo Clinic or
For more information or to participate in this research study, please contact Lori Lutzke at (507) 255-7495.

What is/are the Locations of this Clinical Trial?

• Rochester, MN

Last updated: 10/25/2007